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260684 Sigma-Aldrich

1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem

A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.

Synonym: 1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem, DNJ, HCl

  • CAS Number 73285-50-4

  • Empirical Formula (Hill Notation) C6H13NO4 · xHCl

  • Molecular Weight 163.17 (free base basis)

  •  MDL number MFCD00133247

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Properties

Quality Level   100
assay   ≥98% (TLC)
form   crystalline solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
storage conditions   +2C to +8C
solubility   water: 100 mM
shipped in   ambient

Description

General description

A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.

Specific glucosidase inhibitor, including trimming glucosidases I and II, that sequentially removes the three glucose residues from precursor Glc3Man9GlcNAc2 in N-linked glycan biosynthesis.

Packaging

10 mg in Plastic ampoule

Biochem/physiol Actions

Cell permeable: no

Primary Target
Glucosidase 1, glucosidase 2

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Other Notes

Suh, K., et al. 1992. J. Biol. Chem. 267, 21671.
Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta825, 95.

Safety & Documentation

Safety Information

Protocols & Articles
Peer-Reviewed Papers
15

References

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