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264101 Millipore

Deoxycholic Acid sodium

An ionic detergent for the solubilization of membrane-bound proteins.

Synonym: 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt, Sodium deoxycholate

  • CAS Number 302-95-4

  • Empirical Formula (Hill Notation) C24H39NaO4

  • Molecular Weight 414.55

  •  Beilstein/REAXYS Number 3581950

  •  MDL number MFCD00064139

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Properties

Quality Level   100
assay   ≥96% (TLC)
form   powder
mol wt   micellar avg mol wt 1200-5000
  micellar wt 1700-4200
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
storage conditions   +15C to +30C
aggregation number   3-12
  4 - 10
color   white to off-white
pKa    6.2
CMC   2-6 mM (20-25°C)
  4 - 8 mM
solubility   H2O: 2%, clear, colorless
cation traces   heavy metals: ≤20.0 ppm
HLB   16
shipped in   ambient
SMILES string   [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI   1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1
InChI key   FHHPUSMSKHSNKW-SMOYURAASA-M

Description

General description

An ionic detergent for the solubilization of membrane-bound proteins (aggregation number: 4-10; CMC: 4-8 mM; micellar weight: 1700-4200; pKa 6.2). Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM).

An ionic detergent for the solubilization of membrane-bound proteins. Reported to induce tyrosine phosphorylation of β-catenin and its subsequent translocation to the nucleus, promoting activation of β-catenin signaling (effective concentration 5-50 µM). Aggregation number: 4-10.

Packaging

1 kg in Glass bottle

25, 100 g in Glass bottle

Warning

Toxicity: Harmful (C)

Other Notes

Pai, R., et al. 2004. Mol. Biol. Cell15 2156.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
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