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341578 Sigma-Aldrich

Fibrinogen, Plasminogen-Depleted, Human Plasma

Plasminogen-Depleted fibrinogen is a native fibrinogen from which plasminogen is depleted using a Lys-agarose column. Contains ≥ 95% clottable proteins.

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Properties

Related Categories Auxiliary Proteins, Biochemicals and Reagents, Enzymes, Inhibitors, and Substrates, Other, Proteins and Derivatives More...
packaging   500 mg in Glass bottle (341578-500MG)
feature productdata solubility   H₂O (25 mg/ml). To prevent clot formation, warm the H₂O and the fibrinogen to 37°C prior to dissolution.
brand family   CBC
form   Lyophilized
purity   homogeneous by SDS-PAGE. Clottable proteins: ≥95%
shipped in   1
storage conditions   15
  N

Description

General description

Native fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Contains ≥ 95% clottable proteins.

Native fibrinogen from human plasma, depleted of plasminogen using a Lys-agarose column. An acute-phase plasma protein found at about 300 mg/dl. Conversion of soluble fibrinogen to the insoluble clot-forming fibrin is the terminal stage of blood clotting. Clinically, fibrinogen is found at elevated levels during pregnancy, after surgery trauma, or in cases of myocardial infarction. It is found at decreased levels in cases of liver cirrhosis and serum hepatitis. The plasminogen was depleted using a Lys-agarose column.

Other Notes

Wang, H., et al. 1995. J. Infect. Dis.171, 85.

Reconstitution

Following reconstitution, aliquot and freeze (-70°C) for long term storage or store at room temperature (20°C) for short-term storage. Stock solutions are stable for up to 4 h at 20°C or for up to 6 months at -70°C. Do not store solutions on ice; precipitation will occur. Stock solutions stored at -70°C should be thawed in a water bath maintained at 37°C.

Warning

Harmful (C)

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