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344215 Sigma-Aldrich

Formononetin - CAS 485-72-3 - Calbiochem

A phytoestrogenic isoflavone found in soy-based foods.

Synonym: 7-Hydroxy-3-(4ʹ-methoxyphenyl)-4H-benzopyran-4-one, Formononetin - CAS 485-72-3 - Calbiochem

  • CAS Number 485-72-3

  • Empirical Formula (Hill Notation) C16H12O4

  • Molecular Weight 268.26

  •  MDL number MFCD00016948

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Properties

Related Categories Antioxidant and Free Radical Scavengers, Cancer Research, Cell Biology, Chemopreventive Agents
Quality Level   100
assay   ≥90% (HPLC)
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
  protect from light
storage conditions   -20C
color   white to off-white
solubility   methanol: 2 mg/mL
  DMSO: 200 mg/mL
shipped in   ambient
InChI   1S/C16H12O4/c1-19-12-5-2-10(3-6-12)14-9-20-15-8-11(17)4-7-13(15)16(14)18/h2-9,17H,1H3
InChI key   HKQYGTCOTHHOMP-UHFFFAOYSA-N

Description

General description

A non-steroidal phytoestrogenic isoflavone found in soy-based food products. Has been shown to interact with human estrogen receptor with relatively low potency. Induces mammary gland proliferation in mice. Inhibits lecithin peroxidation induced by hydroxyl radicals. Also acts as a selective inhibitor of γ-isoform of alcohol dehydrogenase.

A phytoestrogenic isoflavone found in soy-based foods. Displays potent antioxidant properties and acts as a selective inhibitor of the γ-isoform of alcohol dehydrogenase. Shown to interact with human estrogen receptors with low potency. Induces mammary gland proliferation in mice.

Packaging

5 mg in Plastic ampoule

Biochem/physiol Actions

Cell permeable: no

Primary Target
Selective inhibitor of the γ-isoform of alcohol dehydrogenase

Product does not compete with ATP.

Reversible: no

Packaging

Packaged under inert gas

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. Do not re-freeze any thawed aliquots.

Other Notes

Pool-Zobel, B.L., et al. 2000. Carcinogenesis 21, 1247.
Toda, S., and Shirataki, Y. 1999. Phytother. Res.13, 163.
Ruiz-Larrea, M.B., et al. 1997. Free Radic. Res.26, 63.
Keung, W.M. 1995. Biochem. Biophys. Res. Commun.215, 1137.
Wang, W., et al. 1995. Nutr. Cancer23, 131.
Miksicek, R.J. 1994. J. Steroid Biochem. Mol. Biol.49, 153.

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
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