• USA Home
  • 345802 - Gc-Globulin, Mixed Type, Human Plasma

EMAIL THIS PAGE TO A FRIEND
345802 Sigma-Aldrich

Gc-Globulin, Mixed Type, Human Plasma

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

Synonym: Gc-Globulin, Mixed Type, Human Plasma

Purchase

Properties

Related Categories Auxiliary Proteins, Biochemicals and Reagents, Other, Proteins and Derivatives
Quality Level   100
assay   ≥95% (SDS-PAGE)
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
storage conditions   -20C
shipped in   ambient

Description

General description

Native Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D. May also play an important role in actin homeostasis as it has been shown to bind monomeric actin with high affinity. Binds to cell surface at the DBP binding site in a nonsaturable manner.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

Packaging

1 mg in Plastic ampoule

Application

Gc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.

Warning

Toxicity: Standard Handling (A)

Physical form

Lyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.

Preparation Note

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.

Other Notes

Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology7, 825.
Machii, T., et al. 1986. Acta Haematol.75, 26.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?