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362338 Millipore

Glyco-SNAP-1 - Calbiochem

A water-soluble nitric oxide (NO) donor.

Synonym: N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide, N-(β-D-Glucopyranosyl)-N²-acetyl-S-nitroso-D,L-penicillaminamide

  • Empirical Formula (Hill Notation) C13H23N3O8S

  • Molecular Weight 381.40

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Properties

Related Categories Application Index, Biochemicals and Reagents, Cell Signaling Enzymes, Enzymes, Inhibitors, and Substrates, Nitric Oxide Metabolism More...
packaging   5 mg in Plastic ampoule (362338-5MG)
feature productdata solubility   H₂O (100 mg/ml), Aqueous Buffers (100 mg/ml), Methanol (5 mg/ml)
brand family   Calbiochem
form   Green crystalline solid
purity   ≥96% by NMR
shipped in   ambient
storage conditions   -20C
  Protect from light
  Ok to freeze

Description

Biochem/physiol Actions

Cell permeable: no

Primary Target
A water-soluble nitric oxide (NO) donor

Product does not compete with ATP.

Reversible: no

General description

A water-soluble and stable nitric oxide (NO) donor (t½ = 28.5-30.2 hr). Glyco-SNAP-1 is more stable than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8-9). The SNAP moiety acts as an NO group donor and the sugar fragment provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes much more slowly in the presence of thiols such as cysteine or glutathione.

A water-soluble nitric oxide (NO) donor. More stable (t½ = 28.5-30.2 hr) than SNAP (Cat. No. 487910) in aqueous solution with or without EDTA and is relatively stable at high pH (pH 8 - 9). The SNAP moiety acts as an NO group donor and the sugar moiety provides hydrophilicity and specificity. Compared to SNAP, glyco-SNAP-1 decomposes at a much slower rate in the presence of thiols such as cysteine or glutathione.

Other Notes

Hou, Y., et al. 1999. Methods Enzymol. 301, 242.
Ramirez, J., et al. 1996. Bioorg. Med. Chem. Lett.6, 2575.

Reconstitution

Unstable in solution; reconstitute just prior to use.

Warning

Standard Handling (A)

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

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Protocols & Articles
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