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  • 371543 - Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem

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371543 Millipore

Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem

Non-hydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs. Stimulates adenylate cyclase activity in sarcolemmal membranes by inactivating Gi proteins.

Synonym: GDP-β-S, 3Li, Guanosine 5ʹ-O-(2-Thiodiphosphate), Trilithium Salt - CAS 97952-36-8 - Calbiochem

  • CAS Number 97952-36-8

  • Empirical Formula (Hill Notation) C10H12N5O10P2S · 3Li

  • Molecular Weight 477.07

  •  MDL number MFCD00057735

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Properties

Quality Level   100
assay   ≥85% (HPLC)
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
storage conditions   -20C
color   white
solubility   water: 50 mg/mL
shipped in   ambient

Description

General description

A nonhydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs.

Non-hydrolyzable GDP analog that competitively inhibits G-protein activation by GTP and GTP analogs. Stimulates adenylate cyclase activity in sarcolemmal membranes by inactivating Gi proteins.

Packaging

20 mg in Plastic ampoule

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions lose 5% of their activity after 6 months at -20°C.

Other Notes

Piacentini, L., et al. 1996. Biochim. Biophys. Acta1282, 11.
Eberhard, D.A. and Holz, R.W., et al. 1991. Biochem J.279, 447.
Silk, S.T., et al. 1989. J. Biol. Chem.264, 21466.
Burch, R.M., et al. 1987. Proc. Natl. Acad. Sci. USA84, 6374.
Gilman, A.G. 1987. Annu. Rev. Biochem.56, 615.
Eckstein, F., et al. 1979. J. Biol. Chem.254, 9829.

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