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407286 Sigma-Aldrich

Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6)

liquid, clone 272-17E6, Calbiochem®

Synonym: Anti-CD51

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Properties

Related Categories Alphabetical Index, Antibodies, IN-IP, Primary Antibodies
clone   272-17E6, monoclonal
biological source   mouse
species reactivity   human
form   liquid
shipped in   wet ice
isotype   IgG1
Quality Level   100
antibody product type   primary antibodies
contains   ≤0.1% sodium azide as preservative
mfr. no.   Calbiochem®
storage condition   OK to freeze
  avoid repeated freeze/thaw cycles
storage conditions   -20C

Description

General description

Purified mouse monoclonal antibody. Recognizes the αv integrin chain and all αv-containing integrins.

Recognizes the αv integrin chain and all αv-containing integrins.

This Anti-Integrin αv (Ab-1) Mouse mAb (272-17E6) is validated for use in Cell Inhibition Assays, ELISA, FC, IP for the detection of Integrin αv (Ab-1).

Immunogen

Human

human placental αvβ₃ integrin

Application

Cell Inhibition Assays (see application reference)

ELISA (see application reference)

Flow Cytometry (2.5 µg/ml, see application reference)

Immunoprecipitation (2.5 µg/ml, see application reference)

Physical form

In PBS, pH 7.6.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Packaging

100 μg in Plastic ampoule

Please refer to vial label for lot-specific concentration.

Warning

Toxicity: Standard Handling (A)

Other Notes

Akiyama, S.K. 1996. Hum. Cell9, 181.
Hynes, R.O. 1992. Cell69, 11.
Albelda, S.M. and Buck, C.A. 1990. FASEB J.4, 2868.
Buck, C.A. and Horwitz, A.F. 1987. Ann. Rev. Cell Biol.3, 179.
Hynes, R.O. 1987. Cell45, 549.

Cross-reacts with all αv integrins. Blocks cell adhesion mediated by all αv integrins and in vivo melanoma growth and angiogenesis (see application references). Variables associated with assay conditions will dictate the proper working dilution.

Safety & Documentation

Safety Information

Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

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