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407299 Sigma-Aldrich

Anti-β-Interferon Rabbit pAb

liquid, clone, Calbiochem®

Synonym: Anti-IFN-β

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Properties

Related Categories Alphabetical Index, Antibodies, B-BI, Primary Antibodies
clone   polyclonal
biological source   rabbit
species reactivity   human
form   liquid
shipped in   wet ice
isotype   IgG
Quality Level   100
antibody product type   primary antibodies
does not contain   preservative
mfr. no.   Calbiochem®
storage condition   OK to freeze
  avoid repeated freeze/thaw cycles
storage conditions   -20C

Description

General description

Rabbit polyclonal antibody supplied as diluted serum. Recognizes the ~20 kDa β-interferon protein.

Recognizes the ~20 kDa IFN-β protein. Note: 1 KU = 1000 neutralization units.

This Anti-β-Interferon Rabbit pAb is validated for use in Neutralization Studies for the detection of β-Interferon.

Immunogen

Human

recombinant, human β-interferon

Application

Neutralization Studies (see application references)

Physical form

Serum diluted in PBS.

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Packaging

20 ku in Plastic ampoule

Biochem/physiol Actions

≥1 x 10⁵ neutralization units/ml

Warning

Toxicity: Standard Handling (A)

Other Notes

Does not recognize α-interferon or γ-interferon by immunoblotting. Effectively neutralizes human β-interferon (see application references). One neutralization unit is the amount of diluted serum required to neutralize 1 unit of human interferon-β. One KU = 1,000 neutralization units. Variables associated with assay conditions will dictate the proper working dilution.

Familletti, P.C., et al. 1981. Methods Enzymol.78, 387.
Rubinstein, S., et al. 1981. J. Virol. 37, 755.

Safety & Documentation

Safety Information

Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

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