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  • 475828 - β₂-Microglobulin, Human, Recombinant, E. coli

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475828 Sigma-Aldrich

β₂-Microglobulin, Human, Recombinant, E. coli

Synonym: rhβ₂M

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Properties

Related Categories Auxiliary Proteins, Biochemicals and Reagents, Other, Proteins and Derivatives
Quality Level   100
form   lyophilized
mfr. no.   Calbiochem®
storage condition   OK to freeze
  avoid repeated freeze/thaw cycles
storage conditions   -20C
solubility   aqueous buffer: soluble
shipped in   wet ice

Description

General description

Recombinant, human β2-microglobulin fused at the N-terminus to a His•Tag sequence and expressed in E. coli. Subsequently cleaved with CNBr to remove the His•Tag sequence. Extracellular protein that is non-covalently associated with the α-chains of class I MHC molecules. Used as a marker for various tumors and for kidney disease. The purified protein functions similarly to the native protein in in vitro models of amyloid fibril extension.

Packaging

1 mg in Plastic ampoule

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following initial thaw, aliquot and freeze (-20°C).

Analysis Note

single band by SDS-PAGE

Other Notes

Sugg, S.V., et al. 1981. Proc. Natl. Acad. Sci. USA 78, 6613.
Berggard, I., and Bearn, G. 1968. J. Biol. Chem. 243, 4095.

Safety & Documentation

Safety Information

Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
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