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480005 Millipore

NDSB-201 - CAS 15471-17-7 - Calbiochem

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.

Synonym: 3-(1-Pyridino)-1-propane Sulfonate, NDSB-201 - CAS 15471-17-7 - Calbiochem

  • CAS Number 15471-17-7

  • Empirical Formula (Hill Notation) C8H11NO3S

  • Molecular Weight 201.24

  •  MDL number MFCD00064468

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Properties

Related Categories Biochemicals and Reagents, Detergents, Non-Detergents Sulfobetaines (NDSB) More...
Quality Level   100
product line   Emprove® Expert
assay   ≥99% (titration)
form   powder
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
storage conditions   +15C to +30C
color   white
solubility   water: 50 mg/mL
shipped in   ambient
InChI   1S/C8H11NO3S/c10-13(11,12)8-4-7-9-5-2-1-3-6-9/h1-3,5-6H,4,7-8H2
InChI key   REEBJQTUIJTGAL-UHFFFAOYSA-N

Description

General description

A member of the class of nondetergent sulfobetaines. Unlike CHAPS and other zwittergents, NDSBs are nondenaturing even at 1 M concentrations. NDSBs have been used to improve the efficiency of solubilization of membrane proteins, to isolate nuclear proteins, to chromatographically purify halophilic proteins in low ionic strength buffers, and to crystallize proteins. They are zwitterionic over a wide pH range and do not absorb significantly in the near UV range. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. NDSBs can be easily removed by dialysis.

A non-detergent sulfobetaine. Reported to prevent protein aggregation and facilitate the renaturation of chemically and thermally denatured proteins. Zwitterionic over a wide pH range. Easily removed by dialysis.

Packaging

25 g in Plastic ampoule

250 g in Glass bottle

Warning

Toxicity: Irritant (B)

Reconstitution

Following reconstitution, store at room temperature. Stock solutions are stable for up to 3 months at room temperature.

Other Notes

Goldberg, M.E., et al. 1996. Folding & Design 1, 21.
Vuillard, L., et al. 1995. Biochem. J. 305, 337.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
WGK Germany 
WGK 1

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