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481486 Sigma-Aldrich

NF-κB SN50M, Cell-Permeable Inactive Control Peptide - Calbiochem

An inactive control for SN50 peptide.

Synonym: (AAVALLPAVLLALLAPVQRNGQKLMP), NF-κB SN50M, Cell-Permeable Inactive Control Peptide - Calbiochem

  • Empirical Formula (Hill Notation) C123H215N33O30S

  • Molecular Weight 2668.29

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Properties

Quality Level   100
assay   ≥97% (HPLC)
form   lyophilized
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
storage conditions   -20C
solubility   water: 5 mg/mL
shipped in   ambient

Description

General description

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Lys363 for Asn and Arg364 for Gly in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

An inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys363 and Gly for Arg364 in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.

Packaging

500 μg in Plastic ampoule

Biochem/physiol Actions

Cell permeable: no

Primary Target
an inactive control for SN50 peptide

Product does not compete with ATP.

Reversible: no

Packaging

Yes

Warning

Toxicity: Standard Handling (A)

Sequence

H-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.

Other Notes

Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.

Legal Information

Sold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
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