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487920 Sigma-Aldrich

S-Nitrosoglutathione - CAS 57564-91-7 - Calbiochem

A utility carrier of nitric oxide.

Synonym: GSNO, SNOG, S-Nitrosoglutathione - CAS 57564-91-7 - Calbiochem

  • CAS Number 57564-91-7

  • Empirical Formula (Hill Notation) C10H16N4O7S

  • Molecular Weight 336.32

  •  MDL number MFCD00214341

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Properties

Quality Level   100
assay   ≥95% (HPLC)
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated (hygroscopic)
  protect from light
storage conditions   -20C
color   pink
solubility   water: 10 mg/mL
shipped in   ambient
InChI   1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1
InChI key   HYHSBSXUHZOYLX-WDSKDSINSA-N

Description

General description

A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

A utility carrier of nitric oxide. Breaks down to produce nitric oxide and a glutathione radical at pH 7.4. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

Packaging

1 set in Glass bottle

50 mg in Plastic ampoule

10 mg in Glass bottle

Packaged under inert gas

Biochem/physiol Actions

Cell permeable: no

Primary Target
A utility carrier of nitric oxide

Product does not compete with ATP.

Reversible: no

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C or for up to 2 h at 4°C.

Reconstitute in cold distilled H₂O (4°C) free of divalent cations other than Ca2+.

Other Notes

Sandau, K., et al. 1996. Cell Signal.8, 173.
Askew, S.C. 1995. Bioorg. Med. Chem.3, 1.
Fehsel, K., et al. 1995. J. Immunol.155, 2858.
de Belder, A.J., et al. 1994. Cardiovasc. Res.28, 691.
Sexton, D.J., et al. 1994. Photochem. Photobiol.59, 463.
Singh, R.J., et al. 1994. FEBS Lett. 360, 47.
Merryman, P.F., et al. 1993. Arthritis Rheum.36, 1414.
Park, J.W., et al. 1993. Biochem. Mol. Biol. Int.30, 885.
Radomski, M.W., et al. 1992. Br. J. Pharmacol.107, 745.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

WGK Germany 
WGK 3
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