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512731 Millipore

Paromomycin Sulfate - CAS 1263-89-4 - Calbiochem

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity.

Synonym: Neomycin E

  • CAS Number 1263-89-4

  • Empirical Formula (Hill Notation) C23H45N5O14 · xH2SO4

  • Molecular Weight 615.63 (free base basis)

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Properties

Related Categories Antibiotics, Biochemicals and Reagents, Cell Culture, Reagents and Supplements, Spectrum of Activity More...
packaging   5 gm in Glass bottle (512731-5GM)
feature productdata solubility   H₂O
brand family   Calbiochem
form   Off-white solid
shipped in   ambient
storage conditions   +15C to +30C
  Ok to freeze

Description

General description

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates paromomycin binding to the A-site of 16S rRNA induces a local conformational change that suggests a mechanism for aminoglycoside action on protein translation.

An aminoglycoside antibiotic containing 5 amino groups that exhibits antibacterial and antiamebic activity. Recent NMR evidence indicates that paromomycin binding to the A-site of 16S rRNA induces a local conformational change, suggesting a mechanism for aminoglycoside action on protein translation. Also exhibits anti-protozoal properties.

Potency: ≥675 µg/mg.

Other Notes

VanLoock, M.S., et al. 1999. J. Mol. Biol. 285, 2069.
Blanchard, S.C., et al. 1998. Biochemistry 37, 7716.
Fourmy, D., et al. 1998. J. Mol. Biol. 277, 333.

Warning

Harmful (C)

Safety & Documentation

Safety Information

RTECS 
WK2320000

Documents

Certificate of Analysis

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Protocols & Articles
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