• USA Home
  • 539560 - PKC Inhibitor Peptide 19-36

EMAIL THIS PAGE TO A FRIEND
539560 Sigma-Aldrich

PKC Inhibitor Peptide 19-36

The PKC Inhibitor Peptide 19-36 controls the biological activity of PKC. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.

Synonym: PKC Inhibitor Peptide 19-36, Protein Kinase C Inhibitor Peptide 19-36, RFARKGALRQKNVHEVKN

  • Empirical Formula (Hill Notation) C93H159N35O24

  • Molecular Weight 2151.48

Purchase

Properties

Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, P to Q,
Quality Level   100
assay   ≥95% (HPLC)
form   lyophilized solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
storage conditions   -20C
color   white to off-white
solubility   water: 0.1%
shipped in   ambient

Description

General description

Acts as pseudosubstrate by binding to the active sites of protein kinase C. A potent, reversible, and substrate competitive inhibitor of protein kinase C (Ki = 147 nM) but not of protein kinase A (IC50 = 423 µM).

Packaging

500 μg in Plastic ampoule

Biochem/physiol Actions

Cell permeable: no

Primary Target
PKC

Product does not compete with ATP.

Reversible: yes

Target Ki: 147 nM against protein kinase C

Packaging

Yes

Warning

Toxicity: Standard Handling (A)

Sequence

H-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-His-Glu-Val-Lys-Asn-OH

Physical form

Supplied as a trifluoroacetate salt.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 weeks at -20°C.

Other Notes

Makowske, M. and Rosen, O.M. 1989. J. Biol. Chem.264, 16155.
House, C. and Kemp, B.E. 1987. Science238, 1726.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?