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5711 Sigma-Aldrich

Streptomycin Sulfate, Streptomyces sp. - CAS 3810-74-0 - Calbiochem

Streptomycin Sulfate, Streptomyces sp., CAS 3810-74-0, is an antibiotic effective against Gram-positive and Gram-negative bacteria. Blocks initiation, elongation, and termination in prokaryotes.

Synonym: Streptomycin Sulfate, Streptomyces sp. - CAS 3810-74-0 - Calbiochem

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Properties

Quality Level   100
form   solid
specific activity   ≥720 U/mg
mfr. no.   Calbiochem®
storage condition   OK to freeze
storage conditions   +15C to +30C
color   white
solubility   water: 50 mg/mL
shipped in   ambient
InChI   1S/2C21H39N7O12.3H2O4S/c2*1-5-21(36,4-30)16(40-17-9(26-2)13(34)10(31)6(3-29)38-17)18(37-5)39-15-8(28-20(24)25)11(32)7(27-19(22)23)12(33)14(15)35;3*1-5(2,3)4/h2*4-18,26,29,31-36H,3H2,1-2H3,(H4,22,23,27)(H4,24,25,28);3*(H2,1,2,3,4)/t2*5-,6-,7+,8-,9-,10-,11+,12-,13-,14+,15+,16-,17-,18-,21+;;;/m00.../s1
InChI key   QTENRWWVYAAPBI-YCRXJPFRSA-N

Description

General description

Antibiotic effective against Gram-positive and Gram-negative bacteria. Often used in culture media to control growth of microorganisms. Inhibits initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code.

Antibiotic effective against gram-positive and gram-negative bacteria. Often used in culture media to control the growth of microorganisms. Inhibits initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code. Suggested working concentration: 25-50 µg/ml.

Packaging

100 g in Glass bottle

Biochem/physiol Actions

Primary Target
initiation, elongation, and termination of protein synthesis in prokaryotes and induces misreading of the genetic code

Warning

Toxicity: Carcinogenic / Teratogenic (D)

Preparation Note

Autoclaved media should be cooled to ≤55°C before adding streptomycin.

Reconstitution

Following reconstitution, sterilize by filtration through a 0.22 µm pore-size filter, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Other Notes

Lech, K. and Brent, R. 1995. in Current Protocols in Molecular Biology, Vol. 1 (Ausubel, F.M., et al., eds.), John Wiley & Sons, New York Unit 1.4.
Maniatis, T., et al. 1989. In Molecular Cloning, A Laboratory Manual, Second Edition. Cold Spring Harbor, New York, p. A.6.
Modolell, J. and Davis, B.D. 1969. Nature224, 345.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
WGK Germany 
WGK 3
Protocols & Articles
Peer-Reviewed Papers
15

References

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