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572201 Millipore

Streptozotocin - CAS 18883-66-4 - Calbiochem

An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.

Synonym: 2-Deoxy-2-(3-methyl-3-nitrosoureido)-D-glucopyranose, Streptozotocin - CAS 18883-66-4 - Calbiochem

  • CAS Number 18883-66-4

  • Empirical Formula (Hill Notation) C8H15N3O7

  • Molecular Weight 265.22

  •  MDL number MFCD00006607

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Properties

Quality Level   100
assay   ≥95% (HPLC)
form   crystalline solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
storage conditions   -20C
color   off-white to pale yellow
solubility   water: soluble
cation traces   heavy metals: ≤5 ppm
shipped in   ambient
InChI   1S/C8H15N3O7/c1-11(10-17)8(16)9-4-6(14)5(13)3(2-12)18-7(4)15/h3-7,12-15H,2H2,1H3,(H,9,16)/t3-,4-,5-,6-,7+/m1/s1
InChI key   ZSJLQEPLLKMAKR-GKHCUFPYSA-N

Description

General description

An N-nitroso-containing compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells. A diabetogenic agent.

An N-nitroso-containing diabetogenic compound that acts as a nitric oxide donor in pancreatic islets. An antibiotic effective against Gram-negative bacteria. Causes DNA alkylation and DNA strand breaks in pancreatic islet cells.

Packaging

1 g in Plastic ampoule

250 mg in Plastic ampoule

Warning

Toxicity: Harmful & Carcinogenic / Teratogenic (E)

Reconstitution

Unstable in solution; reconstitute just prior to use. Following initial thaw, aliquot and freeze (-20°C).

Other Notes

Kroncke, K.D., et al. 1995. Biol. Chem. Hoppe Seyler376, 179.
Kwon, N.S., et al. 1994. FASEB J.8, 529.
Rasschaert, J., et al. 1992. Endocrinology130, 3522.
Bennett, R.A. and Pegg, A.E. 1981. Cancer Res.41, 2786.
Yamamoto, H., et al. 1981. Nature294, 284.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
WGK Germany 
WGK 3
Protocols & Articles
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