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584222 Millipore

Tetrahydrouridine - CAS 18771-50-1 - Calbiochem

Potent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O.

Synonym: Tetrahydrouridine - CAS 18771-50-1 - Calbiochem

  • CAS Number 18771-50-1

  • Empirical Formula (Hill Notation) C9H16N2O6

  • Molecular Weight 248.23

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Properties

Quality Level   100
assay   ≥90% (TLC)
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
  desiccated
  protect from light
storage conditions   -20C
color   white to off-white
solubility   water: 200 mg/mL
shipped in   wet ice
InChI   1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5?,6-,7-,8-/m1/s1
InChI key   UCKYOOZPSJFJIZ-XVKVHKPRSA-N

Description

General description

A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies.

Potent competitive inhibitor of cytidine deaminase. Also available as a 100 mM solution in H2O(Cat. No. 584223).

Packaging

10 mg in Plastic ampoule

Packaged under inert gas

Warning

Toxicity: Standard Handling (A)

Reconstitution

Following reconstitution, aliquot, purge with inert gas, and freeze (-20°C). Aqueous stock solutions (at neutral or basic pH) are stable for up to 3 months at -20°C.

Other Notes

Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun. 206, 486.
Bouffard, D.Y., et al. 1993. Biochem Pharmacol.45, 1857.
Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol.30, 7.
Riva, C., et al. 1992. Chemotherapy38, 358.
Yusa, K., et al. 1992. J. Biol. Chem. 267, 16848.
Hanze, A.R. 1967. J. Am. Chem. Soc.89, 6720.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
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