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625625 Millipore

Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem

Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro.

Synonym: 1-O-α-D-Glucopyranosyl-α-D-glucopyranoside, Trehalose, Dihydrate - CAS 6138-23-4 - Calbiochem

  • CAS Number 6138-23-4

  • Empirical Formula (Hill Notation) C12H22O11 · 2H2O

  • Molecular Weight 378.33

  •  MDL number MFCD00071594

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Monosaccharide More...
Quality Level   100
assay   ≥97.5% (by Assay)
form   solid
mfr. no.   Calbiochem®
storage condition   OK to freeze
storage conditions   +15C to +30C
solubility   water: 100 mg/mL
cation traces   Fe: <5 ppm
  heavy metals: <10 ppm
shipped in   ambient
InChI   1S/C12H22O11.2H2O/c13-1-3-5(15)7(17)9(19)11(21-3)23-12-10(20)8(18)6(16)4(2-14)22-12;;/h3-20H,1-2H2;2*1H2/t3-,4-,5-,6-,7+,8+,9-,10-,11-,12-;;/m1../s1
InChI key   DPVHGFAJLZWDOC-PVXXTIHASA-N

Description

General description

Non-reducing disaccharide that yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration. Reported to prevent myoglobin collapse and preserve its internal mobility.

Non-reducing disaccharide which yields 2 moles of D-glucose upon acid hydrolysis. Inhibits polyglutamine-mediated protein aggregation both in vivo and in vitro. Oral administration of trehalose has been shown to effectively extend lifespan in a murine Huntington disease model. Also known to accumulate in osmotically-stressed cultured bacterial cells and protect against the adverse effects of dehydration.

Packaging

1 kg in Glass bottle

50 g in Glass bottle

Warning

Toxicity: Standard Handling (A)

Other Notes

Sarkar, S., et al. 2007. J. Biol. Chem. In press.
Tanaka, M., et al. 2004. Nat. Med.10, 148.
Sastry, G.M. and Agmon, N. 1997. Biochemistry 36, 7097.

Safety & Documentation

Safety Information

Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
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