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8.00795 Sigma-Aldrich

1,2-Ethanedithiol

for synthesis

Synonym: 1,2-Ethanedithiol

  • CAS Number 540-63-6

  • Empirical Formula (Hill Notation) C2H6S2

  • Molecular Weight 94.20

  •  MDL number MFCD00004892

  •  EC Index Number 208-752-3

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Properties

Quality Level   200
vapor pressure   6.4 hPa ( 20 °C)
potency   120 mg/kg LD50, oral (Rat)
  197 mg/kg LD50, skin (Rabbit)
mp   -41 °C
transition temp   flash point 50 °C
density   1.12 g/cm3 at 20 °C
InChI   1S/C2H6S2/c3-1-2-4/h3-4H,1-2H2
InChI key   VYMPLPIFKRHAAC-UHFFFAOYSA-N
storage conditions   Store below +30°C.

Description

Analysis Note

Assay (GC, area%): ≥ 99.0 % (a/a)
Density (d 20 °C/ 4 °C): 1.123 - 1.126
Identity (IR): passes test

Safety & Documentation

Safety Information

Protocols & Articles

Articles

Fmoc Resin Cleavage and Deprotection

Having successfully synthesized a protected peptide, one is confronted with a difficult task of having to simultaneously detach the peptide from the resin support and remove all the side-chain protec...
Keywords: Alkylations, Amino acid analysis, Catalysis, Centrifugation, Chromatography, Degradations, Evaporation, Filtration, High performance liquid chromatography, Immobilization, Oxidations, Peptide synthesis, Precipitation, Reductions, Reversed-phase chromatography, Silylations, Solid phase peptide synthesis, Solid supported organic synthesis, Solvents, Thin layer chromatography

Protocols

Fmoc SPPS Protocols for Cysteine Peptides

Peptides containing Cys can exist in either reduced (sulfhydryl) or oxidized inter/intra chain disulfide bonded forms. The synthesis of peptides containing Cys, therefore, presents special challenges...
Keywords: Alkylations, Asymmetric synthesis, Buffers, Centrifugation, Coupling reactions, Cyclizations, Eliminations, Evaporation, Filtration, High performance liquid chromatography, Hormones, Iodinations, Oxidations, Peptide synthesis, Purification, Racemizations, Rearrangements, Reductions, Solid phase peptide synthesis, Solvents, Thiolysis

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