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8.17007 SAFC

Polyethylene glycol 6000


Synonym: PEG, Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 6000



Agency/Method   Ph Eur
Quality Level   500
vapor pressure   <0.01 hPa ( 20 °C)
product line   Emprove® Essential
form   waxy solid
autoignition temp.   420 °C
potency   28000 mg/kg LD50, oral (Rat)
  >20000 mg/kg LD50, skin (Rabbit)
pH   5-7 (20 °C, 100 g/L in H2O)
mp   58-63 °C
transition temp   flash point 270 °C
solubility   550 g/L
density   1.2 g/cm3 at 20 °C
SMILES string   C(CO)O
InChI   1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
storage conditions   Store at +15°C to +25°C.


Analysis Note

Identity: passes test
Appearance: white or almost white solid with a waxy or paraffin-like appearance
Appearance of solution: passes test
Acidity,Alkalinity: passes test
Reducing substances: passes test
Density (d 20/20): about 1.080 (50% solution)
Solidification point: 55 - 61 °C
Viscosity (20 °C): 194 - 243 mm²/s
Viskosity (20 °C): 210 - 262 mPa∙s
Formaldehyde: ≤ 30 ppm
Ethylene oxide (GC): ≤ 1 ppm
Dioxane (GC): ≤ 10 ppm
Hydroxyl value: 16 - 22
Average molecular mass: 5600 - 6600
Sulfated ash: ≤ 0.2 %
Water (K. F.): ≤ 1.0 %
Other residual solvents acc. to ICH-guideline are excluded by the manufacturing process.
Elemental impurity specifications have been set considering ICH Q3D (Guideline for Elemental Impurities). Class 1-3 elements are not
likely to be present above the ICH Q3D option 1 limit, unless specified and indicated (*).
Corresponds to Ph Eur

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Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany

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