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8.17043 SAFC

Thimerosal

Ph Eur,BP

Synonym: Thimerosal

  • CAS Number 54-64-8

  • Empirical Formula (Hill Notation) C9H9HgNaO2S

  • Molecular Weight 404.81

  •  MDL number MFCD00013062

  •  EC Index Number 200-210-4

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Properties

Related Categories APIs (Active Pharmaceutical Ingredients) and Excipients, Biopharmaceutical Process Development and Manufacturing, Excipients, Liquid Dosage Forms, Preservatives,
Agency/Method   BP
  Ph Eur
Quality Level   400
  500
potency   75 mg/kg LD50, oral (Rat)
pH   6.7 (20 °C, 10 g/L in H2O)
mp   232-233 °C (decomposition)
transition temp   flash point 250 °C
solubility   1000 g/L
bulk density   450 kg/m3
InChI   1S/C7H6O2S.C2H5.Hg.Na/c8-7(9)5-3-1-2-4-6(5)10;1-2;;/h1-4,10H,(H,8,9);1H2,2H3;;/q;;2*+1/p-2
InChI key   RTKIYNMVFMVABJ-UHFFFAOYSA-L
storage conditions   Store at +15°C to +25°C.

Description

Analysis Note

Assay (Ph Eur, calculated on dried substance): 97.0 - 101.0 %
Identity: passes test
Clarity of solution: passes test
pH-value: 6.0 - 8.0
Ether-soluble substances: ≤ 0.8 %
Free mercury ions: ≤ 0.70 %
Diethyl ether: ≤ 5000 ppm
Ethanol: ≤ 5000 ppm
Other residual solvents (ICH Q3C): excluded by the production process
Loss on drying: ≤ 0.5 %
Readily carbonisable substance: passes test
Corresponds to Ph Eur, BP

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