EMAIL THIS PAGE TO A FRIEND
8.51013 Sigma-Aldrich

HATU

Novabiochem®

Synonym: HATU

  • CAS Number 148893-10-1

  • Empirical Formula (Hill Notation) C10H15N6O · F6P

  • Molecular Weight 380.23

  •  MDL number MFCD27957364

Purchase

Properties

Quality Level   300
mfr. no.   Novabiochem®
mp   186 °C (decomposes)
InChI   1S/C10H15N6O/c1-14(2)10(15(3)4)17-16-9-8(12-13-16)6-5-7-11-9/h5-7H,1-4H3/q+1
InChI key   WXIONIWNXBAHRU-UHFFFAOYSA-N
storage conditions   Store at +2°C to +8°C.

Description

General description

A highly efficient coupling reagent for solid and solution phase peptide synthesis. In comparative studies HATU has been found to give better coupling yields with less enantiomerization that HBTU, TBTU or PyBOP® [1-3]. It is particularly effective at coupling to N-alkyl amines where other coupling reagents give poor yields and is the preferred reagent for loading resins bearing secondary amino groups.

The product number for this product was previously 01-62-0041.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.

Linkage

Replaces: 01-62-0041

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

PyBOP is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Protocols & Articles

Articles

Peptide Coupling Reagents Selection Guide

The Novabiochem® brand offers one of the most extensive ranges of high-quality coupling reagents for in situ activation on the market. However, with such a plethora of reagents available, the choice ...
Keywords: Condensations, Coupling reactions, Cyclizations, Racemizations, Solid phase peptide synthesis

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?