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  • 8.52097 - Fmoc-Lys(biotin)-OH

8.52097 Sigma-Aldrich



Synonym: Fmoc-Lys(biotin)-OH, N-α-Fmoc-N-ε-biotinyl-L-lysine

  • CAS Number 146987-10-2

  • Empirical Formula (Hill Notation) C31H38N4O6S

  • Molecular Weight 594.72

  •  MDL number MFCD00270741



Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Lysine, Peptide Synthesis and Peptide Chemistry More...
Quality Level   200
assay   ≥85.0% (HPLC)
  ≥95% (TLC)
form   powder
mfr. no.   Novabiochem®
application(s)   peptide synthesis: suitable
functional group   Fmoc
storage conditions   Store below +30°C.


General description

A modified lysine derivative for the preparation of biotin-labeled peptides by Fmoc SPPS.

The product number for this product was previously 04-12-1237.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.


Replaces: 04-12-1237

Analysis Note

Color (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA2)): ≥ 95 %
Assay (HPLC, area%): ≥ 85.0 % (a/a)
Solubility (0,1 mmole in 1 ml NMP): clearly soluble
Water (K. F.): ≤ 3.0 %
This product can contain up to 10% DMF in order to assure an ideal solubility.
For TLC-Systems see our General Catalog

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles


Biotinylation Reagents

Biotin-labeled peptides have many important applications in immunology and histochemistry, such as affinity purification1 and FRET-based flow cytometry2, solid-phase immunoassays3, and receptor local...
Keywords: Biotinylations, Immobilization, Immunology, Ligands, Normal-phase chromatography, Solvents

Solvent Systems for Thin-layer Chromatography of Novabiochem Products

The table below lists the solvent systems used for the thin-layer chromatography (TLC) assay of Novabiochem products. To determine the system used, just look up the solvent system code printed adjace...
Keywords: Chromatography, Solvents, Thin layer chromatography

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907251 H-L-Photo-lysine HCl, ≥98%
907383 Fmoc-L-Photo-Lysine, ≥95%
914436 Fmoc-D-Lys(Biotin)-OH, ≥95%

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