8.52099 Sigma-Aldrich



Synonym: Fmoc-Lys(Dnp)-OH, N-α-Fmoc-N-ε-2,4-dinitrophenyl-L-lysine

  • CAS Number 148083-64-1

  • Empirical Formula (Hill Notation) C27H26N4O8

  • Molecular Weight 534.52



Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Lysine, Peptide Synthesis and Peptide Chemistry More...
Quality Level   200
assay   ≥97.0% (HPLC)
  ≥98% (TLC)
form   powder
mfr. no.   Novabiochem®
application(s)   peptide synthesis: suitable
functional group   Fmoc
storage conditions   Store at -15°C to -25°C.


General description

A modified lysine derivative for the preparation of chromogenically-labeled peptides by Fmoc chemistry.

The Dnp group is the preferred quencher for use in conjunction with the Mca fluorophore, making it an extremely useful tool for the synthesis of fluorescence-quenched peptide substrates.

The product number for this product was previously 04-12-1239.

To obtain a certificate of analysis (CoA) of a lot that begins with the letter “A”, please select the option in the right hand menu “Request a COA for Lot#s starting with A”.


Replaces: 04-12-1239

Analysis Note

Color (visual): slight yellow to yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in DMF): -13.5 - -10.5 °
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 97.0 % (a/a)
For TLC-Systems see our General Catalog

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles


Solvent Systems for Thin-layer Chromatography of Novabiochem Products

The table below lists the solvent systems used for the thin-layer chromatography (TLC) assay of Novabiochem products. To determine the system used, just look up the solvent system code printed adjace...
Keywords: Chromatography, Solvents, Thin layer chromatography

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