8.52326 Sigma-Aldrich



Synonym: Fmoc-azidolysine

  • CAS Number 159610-89-6

  • Empirical Formula (Hill Notation) C21H22N4O4

  • Molecular Weight 394.42



Related Categories Amino Acids & Derivatives, Chemical Biology, Chemical Synthesis, Lysine, Peptide Synthesis and Peptide Chemistry More...
Quality Level   200
assay   ≥98.0% (HPLC)
form   powder
mfr. no.   Novabiochem®
application(s)   peptide synthesis: suitable
functional group   Fmoc
storage conditions   Store at -15°C to -25°C.


General description

A useful tool for the synthesis of branched, side-chain modified and cyclic peptides by Fmoc SPPS. The side-chain azido group is completely stable to piperidine and TFA, but can be readily converted to an amine on the solid phase or in solution by reduction with thiols [1] or phosphines [2, 3].

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles


Selecting Orthogonal Building Blocks

Novabiochem® product range has one of the largest collections of orthogonally and quasi-orthogonally protected tri-functional amino acids. These derivatives are useful tools for the synthesis of cycl...
Keywords: Acylations, Catalysis, Combinatorial synthesis, Cyclizations, Eliminations, Filtration, High performance liquid chromatography, Peptide synthesis, Reductions, Solid phase peptide synthesis, Thiolysis

Solvent Systems for Thin-layer Chromatography of Novabiochem Products

The table below lists the solvent systems used for the thin-layer chromatography (TLC) assay of Novabiochem products. To determine the system used, just look up the solvent system code printed adjace...
Keywords: Chromatography, Solvents, Thin layer chromatography

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907251 H-L-Photo-lysine HCl, ≥98%
907383 Fmoc-L-Photo-Lysine, ≥95%

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