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GF113 Sigma-Aldrich

Transforming Growth Factor-β2 Protein, Recombinant human

Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.

Synonym: TGF-beta2

  •  eCl@ss 32160405

  •  NACRES NA.75

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Properties

biological source   human
application(s)   cell analysis: suitable (cell culture)
shipped in   dry ice
Quality Level   100
assay   >95% (SDS-PAGE)
activity   ≥5 x 10e6 U/mg
mfr. no.   Chemicon®
impurities   <0.1 ng/μg Endotoxin (of TGF-Beta2; 1EU/ug)
input   sample type mesenchymal stem cell(s)
NCBI accession no.   NM_003238.1
UniProt accession no.   P61812
Gene Information   human ... TGFB2(7042)

Description

General description

Product Source: Baculovirus infected High-5 cells

Transforming Growth Factor- beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta2 is a 25.0 kDa protein with each subunit containing 112 amino acid residues.

Physical form

Lyophilized from Sodium Citrate, pH 3.5.

Storage and Stability

The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute with water to a concentration of 50 μg/ml (e.g., 5 μg/100 μl), this will yield a solution of 1 mM citrate buffer pH 3.5 This solution can then be stored at room temperature or at 2-8ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at -20ºC. Reconstituted human TGF-beta2 should be stored in undiluted aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells.The ED(50) was found to be <=0.2ng/ml

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
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