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AB10081 Sigma-Aldrich

Anti-CYP2D6 Antibody

Anti-CYP2D6 Antibody detects level of CYP2D6 & has been published & validated for use in WB.

Synonym: Cytochrome P450 2D6

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Properties

Related Categories Antibodies, Primary Antibodies More...
trade name   Chemicon
brand family   Chemicon
format   Serum
molecular weight   58kDa
application(s)   Western Blotting
isotype   IgG2b
clone   Polyclonal Antibody
host   Rabbit
species reactivity   Human
NCBI accession no.   NM_000106.4, NM_001025161.1
UniProt accession no.   P10635
gene symbol   CYP2D6(1565)
  CPD6
  CYP2D
  CYP2D@
  CYP2DL1
  CYPIID6
  MGC120389
  MGC120390
  P450-DB1
  P450C2D
material size   50 µL
shipped in   wet ice
storage conditions   Maintain at 2-8°C for up to 12 months from date of receipt.

Description

Background information

Cytochrome P450 2D6 (CYP2D6), a member of the cytochrome P450 mixed-function oxidase system, is one of the most important enzymes involved in the metabolism of xenobiotics in the body. Whilst CYP2D6 is involved in the oxidation of a wide range of substrates of all the CYPs, there is considerable variability in its expression in the liver.

Physical form

Raw rabbit serum with 0.1% sodium azide.

Application

Suggested dilutions:
Western Blot: 1:5000

Immunogen

Recombinant human CYP2D6

Quality Assurance

Routinely evaluated by immunoblot.

Usage Statement

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

Peer-Reviewed Papers
15

References

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