AB2960 Sigma-Aldrich

Anti-UVRAG Antibody

clone, from rabbit, purified by affinity chromatography

Synonym: UV radiation resistance-associated gene protein, p63

  •  eCl@ss 32160702

  •  NACRES NA.41



Related Categories Alphabetical Index, Antibodies, Primary Antibodies, UH-UZ
clone   polyclonal
biological source   rabbit
application(s)   immunocytochemistry: suitable
  immunoprecipitation (IP): suitable
  western blot: suitable
species reactivity   mouse, human, rat
shipped in   wet ice
Quality Level   100
antibody product type   primary antibodies
purified by   affinity chromatography
NCBI accession no.   NP_003360
UniProt accession no.   Q9P2Y5
Gene Information   human ... UVRAG(7405)


General description

UV irradiation resistance-associated gene (UVRAG) is an essential component of the Beclin1-PI(3)KC3 lipid kinase complex which functions as an important signaling checkpoint for autophagy and tumor-cell growth. More specifically, UVRAG seems to work as a multivalent trafficking effector that controls autophagosome formation and maturation, and also controls the engaging of the fusion apparatus to the endosome. UVRAG may be a promising target for cancer therapies.


This antibody recognizes the C-terminus of UVRAG.


Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human UVRAG.


Anti-UVRAG Antibody is an antibody against UVRAG for use in WB, IC & IP.

Immunoprecipitation Analysis: 10 µg from a representative lot immunoprecipitated UVRAG from 500 µg from Raji cell lysate.

Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected UVRAG in NIH/3T3 and A431 cells.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Target description

~78 kDa observed

Physical form

Affinity Purfied

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


Evaluated by Western Blot in Raji cell lysate.

Western Blot Analysis: 0.1 µg/mL of this antibody detected UVRAG in 10 µg of Raji cell lysate.

Analysis Note

Raji cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety & Documentation

Safety Information

WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Autophagy and Mitophagy in Tumor Cell Survival and Death

Autophagy is a highly regulated process that is involved in cell growth, development, and death. In autophagy cells destroy their own cytoplasmic components in a very systematic manner and recycle th...
Chandra Mohan, Ph.D.
MilliporeSigma, Temecula, CA
Keywords: Apoptosis, Autophagy, Bacterial conjugations, Cancer, Cell proliferation, Degradations, Diseases, Immunofluorescence, Oxidations, Phosphorylations, Reductions, Separation, Ubiquitinations, Western blot


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

Related Content

Antibody Explorer | Buy Primary Antibodies & Secondary Antibodies

Primary, Secondary and Recombinant Monoclonal Antibodies Providing highly cited primary and secondary antibodies, we have you covered for your ELISA, western blot, immunohistochemistry or other assay...
Keywords: Alzheimer Disease, Cancer, Chromatin immunoprecipitation, Diagnostic, Enzyme-linked immunosorbent assay, Flow cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Neuroscience, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?