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  • ABT333 - Anti-IL-1RAcP Antibody

ABT333 Sigma-Aldrich

Anti-IL-1RAcP Antibody

Detect Interleukin Receptor using this rabbit polyclonal antibody, Anti-IL-1RAcP Antibody validated for use in western blotting & ICC.

Synonym: IL-1RAcP, C3orf13, IL1R3, Interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, IL-1RAcP, Interleukin-1 receptor 3

  •  eCl@ss 32160702



Related Categories Antibodies, Primary Antibodies More...
gene symbol   IL1RAP(3556)
UniProt accession no.   Q9NPH3
Quality Assurance   Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected IL-1RAcP in 15 µg of HeLa cell lysate.
application(s)   Western Blotting, Immunocytochemistry
clone   Polyclonal Antibody
concentration   Please refer to the Certificate of Analysis for the lot-specific concentration.
format   Affinity Purified
host   Rabbit
molecular weight   ~66 kDa observed. Uncharacterized bands may appear in some lysate(s).
packaging   100 µg (ABT333)
shipped in   wet ice
species reactivity   Human



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Analysis Note

HeLa cell lysate


Immunocytochemistry Analysis: 5 ug/mL from a representative lot detected IL-1RAcP in HeLa cells.

Research Category
Cell Structure

Research Sub Category
Cytokines & Cytokine Receptors

General description

Interleukin-1 receptor accessory protein (IL-1RAcP), also known as Interleukin-1 receptor 3 (IL-1R-3, IL-1R3) forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruites to the IL-1R complex through IL-1 RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.


Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human IL-1RAcP.


This antibody recognizes the C-terminus of IL-1RAcP.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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