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ABT333 Sigma-Aldrich

Anti-IL-1RAcP Antibody

Detect Interleukin Receptor using this rabbit polyclonal antibody, Anti-IL-1RAcP Antibody validated for use in western blotting & ICC.

Synonym: IL-1RAcP, C3orf13, IL1R3, Interleukin-1 receptor accessory protein, IL-1 receptor accessory protein, IL-1RAcP, Interleukin-1 receptor 3

  •  eCl@ss 32160702

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Properties

Related Categories Antibodies, Primary Antibodies More...
gene symbol   IL1RAP(3556)
  IL-1R-3
  IL-1R3
UniProt accession no.   Q9NPH3
Quality Assurance   Evaluated by Western Blotting in HeLa cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected IL-1RAcP in 15 µg of HeLa cell lysate.
application(s)   Western Blotting, Immunocytochemistry
clone   Polyclonal Antibody
concentration   Please refer to the Certificate of Analysis for the lot-specific concentration.
format   Affinity Purified
host   Rabbit
molecular weight   ~66 kDa observed. Uncharacterized bands may appear in some lysate(s).
packaging   100 µg (ABT333)
shipped in   wet ice
species reactivity   Human

Description

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Analysis Note

Control
HeLa cell lysate

Application

Immunocytochemistry Analysis: 5 ug/mL from a representative lot detected IL-1RAcP in HeLa cells.

Research Category
Cell Structure

Research Sub Category
Cytokines & Cytokine Receptors

General description

Interleukin-1 receptor accessory protein (IL-1RAcP), also known as Interleukin-1 receptor 3 (IL-1R-3, IL-1R3) forms a complex with IL-1RI in response to IL-1 treatment. The IL-1 receptor-associated kinase (IRAK), which mediates activation of NF-kB inducing kinae (NIK) and of NF-kB, recruites to the IL-1R complex through IL-1 RAcP. IL-1 activation of stress-activated protein kinase and of acid sphingomyelinase also requires IL-1RAcP. Like IL-1RI, IL-1RAcP subunit is essential for IL-1 mediated cellular response. IL-1RAcP is expressed in many tissues.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human IL-1RAcP.

Specificity

This antibody recognizes the C-terminus of IL-1RAcP.

Physical form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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