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AG270 Sigma-Aldrich

Neurocan, chicken

  •  eCl@ss 32160702

  •  NACRES NA.41

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Properties

biological source   chicken
application(s)   ELISA: suitable
  cell analysis: suitable (cell culture)
shipped in   dry ice
mfr. no.   Chemicon®
concentration   100 μg/mL
NCBI accession no.   NM_004386.2
UniProt accession no.   O14594
Gene Information   human ... NCAN(1463)

Description

General description

Neurocan, chicken.

Product Source: Chicken Brain.

Application

Inhibition of cell-cell adhesion, cell-ECM adhesion or cell migration at:

0.1 to 30 micrograms / mL.

ELISA Assay: 0.05 to 5 micrograms / mL

Optimal working concentrations must be determined by the end user.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Physical form

Purified Neurocan in PBS. Contains no preservative.

Storage and Stability

Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Analysis Note

A mix of Chondroitin Sulfate Proteoglycans from chick brain (Chemicon CC117) was purified by the unique density and size of this class of molecules. Neurocan is purified from this mix using an immobilized monoclonal antibody. The resulting neurocan is pure and has chondroitin sulfate attached. Removing the chondroitin sulfate with chondroitinase, results in core proteins are primarily the full-length 250 kD form and a little of smaller neurocan fragments.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles
Peer-Reviewed Papers
15

References

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