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  • AP512 - Sheep Anti-Human IgM, (Fc) Antibody

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AP512 Sigma-Aldrich

Sheep Anti-Human IgM, (Fc) Antibody

clone, Chemicon®, from sheep

Synonym: Ig mu chain C region

  •  eCl@ss 32160702

  •  NACRES NA.46

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Properties

Related Categories Antibodies, Human IgM Secondary Antibodies and Conjugates, Secondaries listed by Conjugate, Secondaries listed by Target Species, Secondary Antibodies,
Quality Level   100
biological source   sheep
antibody product type   secondary antibodies
clone   polyclonal
species reactivity   human, human
mfr. no.   Chemicon®
application(s)   ELISA: suitable
shipped in   wet ice

Description

General description

Immunoglobin M (IgM) antibody is prominent in early immune responses to most antigens and is the predominant response in certain antibody responses such as "natural" blood group antibodies. IgM is the major immunoglobin expressed on surface B lymphocytes. Most of the chronic lymphocytic leukemias, non Hodgkin lymphomas and Burkitt′s lymphoma bear surface IgM, whereas plasmocytes from Waldenström′s disease bear intracytoplasmic IgM.

Specificity

No reactivity with IgG or IgA. May react with IgM of other species with low specificity.

This antibody reacts with human IgM, (Fc) as demonstrated by ELISA.

Immunogen

Epitope: IgM, (Fc)

Human anti-Human IgM (myeloma) Fc5u fragment

Application

Research Category
Secondary & Control Antibodies

Research Sub Category
Isotype Control Antibodies

Sheep anti-Human IgM, (Fc) Antibody is an antibody against Human IgM, (Fc) for use in ELISA.

Quality

Evaluated by ELISA against Human IgG, Human IgG Fab Fragment, Human IgG Fc, Human IgM Fc, Human IgM (myeloma) Fab m fragment, Human IgA, Mouse IgM, Rat IgM whole molecule, Chicken IgM whole molecule, Goat IgM whole molecule, Guinea Pig IgM whole molecule, Hamster IgM whole molecule, and Rabbit IgM whole molecule.

ELISA Analysis: A representative lot detected Sheep Anti-Human IgM, (Fc) in ELISA.

Target description

50 kDa calculated

Physical form

Depletion

Format: Purified

Purified sheep polyclonal in PBS containing 0.05% sodium azide. Depleted against rabbit IgM and human IgG.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Human IgG, Human IgG Fab Fragment, Human IgG Fc, Human IgM Fc, Human IgM (myeloma) Fab m fragment, Human IgA, Mouse IgM, Rat IgM whole molecule, Chicken IgM whole molecule, Goat IgM whole molecule, Guinea Pig IgM whole molecule, Hamster IgM whole molecule, and Rabbit IgM whole molecule

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

WGK Germany 
WGK 2
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

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