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  • FCMAB255F - Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1

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FCMAB255F Sigma-Aldrich

Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1

Milli-Mark Anti-Mouse IL-17 FITC Antibody, clone TC11-18H10.1 detects level of Mouse IL-17 & has been published & validated for use in FC.

Synonym: Cytotoxic T-lymphocyte-associated antigen 8

  •  eCl@ss 32160702

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Properties

Related Categories Antibodies, Primary Antibodies More...
gene symbol   Il17a
NCBI accession no.   NP_034682
UniProt accession no.   Q62386
Quality Assurance   Evaluated by flow cytometry using stimulated EL-4 cells
application(s)   Flow Cytometry
clone   Monoclonal Antibody
  TC11-18H10.1
format   FITC
host   Rat
isotype   IgG1κ
molecular weight   17 kDa Calculated
packaging   100 tests (FCMAB255F)
shipped in   wet ice
species reactivity   Mouse
trade name   Milli-Mark

Description

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Analysis Note

Control
PMA and Ionomycin stimulated EL-4 cells.

Application

Research Category
Inflammation & Immunology

Research Sub Category
Immunological Signaling

General description

IL17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL1beta, IL6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL17are significantly increased and may contribute to bone destruction.

Immunogen

Recombinant protein corresponding to mouse Il17a

Specificity

Antibody recognizes Interleukin-17A.

Physical form

Antigen Affinity Purified

Purified rat monoclonal IgG1κ conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Storage and Stability

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles
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