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GF007 Sigma-Aldrich

Insulin-like Growth Factor-II Protein, Recombinant human

The Insulin Like Growth Factor-II protein (or IGF-2 protein) is a polypeptide growth factor which stimulates the proliferation of a wide range of cell types.

Synonym: IGF-II

  •  eCl@ss 32160405

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Properties

biological source   human
application(s)   cell analysis: suitable (cell culture)
shipped in   dry ice
assay   >98% (SDS-PAGE and HPLC)
activity   ≥5 x 105 U/mg
mfr. no.   Chemicon®
input   sample type mesenchymal stem cell(s)
NCBI accession no.   NM_000612.3
  NM_001007139.3
UniProt accession no.   P01344
Gene Information   human ... IGF2(3481)

Description

General description

Insulin Like Growth Factor-II (IGF-II) is a polypeptide growth factor which stimulates the proliferation of a wide range of cell types. Human IGF-II is a 7.5 kDa protein containing 67 amino acid residues.

Product Source: E.coli

Application

For most in vitro applications, IGF-II exerts its biological activity in the concentration range of 0.5 to 25.0 ng/mL. Responding cells are (partial list): Bone, muscle cells.

Optimal working dilutions must be determined by end user.

Optimal working dilutions must be determined by end user.

Physical form

Lyophilized powder with no additives

Storage and Stability

The lyophilized IGF-II, though stable at room temperature, is best stored at -20°C. After a quick spin, reconstitute in water to a concentration of 0.1-1.0 mg/mL. This solution can be diluted into other buffered solutions. Reconstituted IGF-II should be stored in undiluted aliquots at -20°C for up to six months. Avoid repeated freeze/thaw cycles.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Analysis Note

Specific Activity: Chemicon′s Human IGF-II is fully biologically active when compared to standards.The ED50 as determined by a cell proliferation assay using FDC-P1 cells is <= 2.0 ng/mL

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
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