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IL012 Sigma-Aldrich

Interleukin-13 Protein, Recombinant human

The recombinant human Interleukin-13 protein (or IL-13 protein) is a immunoregulatory protein produced by activated T-lymphocytes.

Synonym: IL-13

  •  eCl@ss 32160405

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines and Growth Factors,
packaging   10 µg (IL012)
gene symbol   ALRH(260328)
  IL13(3596)
trade name   Chemicon
brand family   Chemicon
application(s)   Cell Culture
specific activity   The ED(50) as determined by the dose-dependent proliferation of TF-1 cells was <= 1.0 ng/mL, corresponding to a specific activity of >= 1 x 10(E6) units/mg.
purity   Greater than 98% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/μg) of IL-13.
species   Human
NCBI accession no.   NM_002188.2
UniProt accession no.   P35225
gene symbol   BHR1
  IL-13
  MGC116786
  MGC116788
  MGC116789
  NC30
  P600
shipped in   2

Description

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Application

For most in vitro applications, IL-13 exerts its biological activity in the concentration range of 0.1 to 10.0 ng/mL. Responding cells are (partial list): B-cells, monocytes.

General description

Interleukin-13 (IL-13) is a immunoregulatory protein produced by activated T-lymphocytes. The biological activities of IL-13 include the stimulation of B-cell proliferation and immunoglobulin production and induction of differentiation of B-cells and cells of monocytic lineage. Human IL-13 is a 12.5 kDa protein containing 114 amino acid residues.

Product Source: Human

Physical form

The sterile filtered solution was lyophilized from 20 mM Sodium Phosphate, pH 7.0.

Storage and Stability

The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. After a quick spin, reconstitutein water to a concentration of 0.1-1.0 mg/mL. Note: Slow to dissolve. This solution can be diluted into other buffered solutions and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted human IL-13 should be stored in undiluted aliquots at -20°C for up to six months. Avoid repeated freeze/thaw cycles.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
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