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  • MAB2613 - Anti-UPAR-Associated Protein Antibody, clone 2.h.9:F12

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MAB2613 Sigma-Aldrich

Anti-UPAR-Associated Protein Antibody, clone 2.h.9:F12

clone 2.h.9:F12, from mouse

Synonym: CD280, Endocytic receptor 180, Macrophage mannose receptor 2, UPAR-associated protein, Urokinase receptor-associated protein, Endocytic receptor 180, C-type mannose receptor 2

  •  eCl@ss 32160702

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, Primary Antibodies, UH-UZ
clone   2.h.9:F12, monoclonal
biological source   mouse
application(s)   immunohistochemistry: suitable
  western blot: suitable
species reactivity   human, mouse, mouse, human
shipped in   wet ice
isotype   IgG1κ
Quality Level   100
antibody product type   primary antibodies
NCBI accession no.   NP_006030.2
UniProt accession no.   Q9UBG0
Gene Information   human ... MRC2(9902)

Description

General description

Urokinase plasminogen activator receptor-associated protein (uPARAP/Endo180/MRC2) is a member of the macrophage mannose receptor family of endocytic transmembrane glycoproteins. UPAR-Associated Protein is a membrane protein involved in matrix turnover during tissue remodeling, particularly the uptake and intracellular degradation of collagen, (Sulek, 2007).

Specificity

The antibody recognizes UPAR-Associated Protein.

Immunogen

uPAR D3-tagged recombinant protein corresponding to human UPAR-Associated Protein.

Application

Anti-UPAR-Associated Protein Antibody, clone 2.h.9:F12 is an antibody against UPAR-Associated Protein for use in WB, IH.

Target description

~ 180 kDa

Physical form

Format: Purified

Quality

Evaluated by Western Blot in U937 cell lysate.

Western Blot Analysis: 0.2 µg/ml of this antibody detected UPAR-Associated Protein on 10 µg of U937 cell lysate.

Analysis Note

Control
U937 cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety & Documentation

Safety Information

WGK Germany 
WGK 1
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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