• USA Home
  • MAB354 - Anti-Somatostatin Antibody, clone YC7

EMAIL THIS PAGE TO A FRIEND
MAB354 Sigma-Aldrich

Anti-Somatostatin Antibody, clone YC7

culture supernatant, clone YC7, Chemicon®

  •  eCl@ss 32160702

  •  NACRES NA.41

Purchase

Properties

Related Categories Alphabetical Index, Antibodies, Primary Antibodies, SO-SO
clone   YC7, monoclonal
biological source   rat
application(s)   immunohistochemistry: suitable
species reactivity   rat, human, rabbit
shipped in   dry ice
antibody form   culture supernatant
isotype   IgG2b
Quality Level   100
antibody product type   primary antibodies
mfr. no.   Chemicon®
NCBI accession no.   NM_001048.3
UniProt accession no.   P61278
Gene Information   human ... SST(6750)

Description

General description

Somatostatin (also known as growth hormone inhibiting hormone (GHIH) or somatotropin release-inhibiting factor (SRIF) has two active forms, 14 amino acids and 28 amino acids, which are produced by alternate cleavage of the single preproprotein. Somatostatin is expressed widely and acts to inhibit the release of several secondary hormones by binding to high-affinity G-protein coupled somatostatin receptors. Presence of somatostatin has been shown in sympathetic nerves, mucosal cells, myenteric nerves of the gastrointestinal tract, salivary glands and in some parafollicular cells of the thyroid.

Specificity

Recognizes Somatostatin. Shows no cross-reactivity to enkephalins, other endorphins, substance P or CGRP. Partially cross-reacts with somatostatin fragments.

Immunogen

Synthetic peptide corresponding to amino acids 1-14 of cyclic somatostatin conjugated to bovine thyroglobulin using carbodiimide.

Application

Anti-Somatostatin Antibody, clone YC7 is an antibody against Somatostatin for use in IH.

Immunohistochemistry at 1:50-1:100 on human brain.

Optimal working dilutions must be determined by the end user.

Physical form

Lyophilized Supernatant, preservative free.

Storage and Stability

Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Analysis Note

Control
Pancreas, Brain

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
WGK Germany 
WGK 2
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Related Content

Antibody Explorer | Buy Primary Antibodies & Secondary Antibodies

Primary, Secondary and Recombinant Monoclonal Antibodies Providing highly cited primary and secondary antibodies, we have you covered for your ELISA, western blot, immunohistochemistry or other assay...
Keywords: Alzheimer Disease, Cancer, Chromatin immunoprecipitation, Diagnostic, Enzyme-linked immunosorbent assay, Flow cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Neuroscience, Western blot

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?