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MABF146C Sigma-Aldrich

Anti-CD45 (Mouse), PE-Cy7, clone 30-F11 Antibody

This rat monoclonal Anti-CD45 Antibody (Mouse), PE-Cy7, clone 30-F11, Cat. No. MABF1465 is validated for use in Flow Cytometry, for the detection of CD45.

Synonym: Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen (L-CA), Lymphocyte antigen 5 (Ly-5), T200, CD45, CD45

  •  eCl@ss 32160702

  •  NACRES NA.44

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Properties

Related Categories Antibodies, Primary Antibodies More...
packaging   100 μg (MABF1465)
  25 μg (MABF1464)
application(s)   flow cytometry: suitable
biological source   rat
clone   30-F11, monoclonal
isotype   IgG2bκ
species reactivity   mouse
clone   Monoclonal Antibody
concentration   Please refer to lot specific datasheet.
gene symbol   Ly-5
  Ptprc
conjugate   PE-Cy7
Quality Assurance   This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.125 μg from a representative lot detected CD45 in one million C57Bl/6 splenocytes.

Description

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Application

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

General description

The 30-F11 antibody reacts with mouse CD45, which is one of the most abundant hematopoietic markers and is expressed on all leukocytes (the Leukocyte Common Antigen, LCA). CD45 is a protein tyrosine phosphatase existing in several isoforms, each being generated and expressed in cell-specific patterns. With its broad cell distribution, CD45 is critical for many leukocyte functions, regulating signal transduction and cell activation associated with the T cell receptor, B cell receptor, and IL-2 receptor. Other forms of CD45, with restricted cellular expression, include CD45R (B220), CD45RA, CD45RB, CD45RO and others. The 30-F11 antibody is widely used as a leukocyte marker for B cells, T cell subsets and NK cell subsets.

Immunogen

Immunogen information for this antibody is proprietary information.

Other Notes

Concentration: Please refer to lot specific datasheet.

Physical form

Purified Rat monoclonal containing 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, 0.1% gelatin, pH7.2.

Purified by size-exclusion chromatography

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.
Note: It is recommended to store the product undiluted at 2-8°C and protected from prolonged exposure to light. Do not freeze.

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

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Protocols & Articles
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