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MABF752 Sigma-Aldrich

Anti-CD26, clone EPR5883(2), Rabbit Monoclonal Antibody

clone EPR5883(2), from rabbit

Synonym: Dipeptidyl peptidase 4, ADABP, Adenosine deaminase complexing protein 2, ADCP-2, Dipeptidyl peptidase IV, DPP IV, T-cell activation antigen CD26, TP103, CD antigen CD26, DPP4, ADCP2, CD26

  •  eCl@ss 32160702

  •  NACRES NA.41

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Properties

Related Categories Alphabetical Index, Antibodies, CD0-CDC, Primary Antibodies
clone   EPR5883(2), monoclonal
biological source   rabbit
application(s)   western blot: suitable
species reactivity   human
shipped in   wet ice
isotype   IgG
Quality Level   100
antibody product type   primary antibodies
UniProt accession no.   P27487
Gene Information   human ... DPP4(1803)

Description

General description

Dipeptidyl peptidase 4, also known as ADABP or Adenosine deaminase complexing protein 2 or ADCP-2 or Dipeptidyl peptidase IV or DPP IV or T-cell activation antigen CD26 or TP103 or CD26 , and encoded by the gene name DPP4 or ADCP2 or CD26, is identical to adenosine deaminase complexing protein-2, and to the T-cell activation antigen CD26. CD26 acts as a positive regulator of T-cell coactivation, by binding at least ADA, CAV1, IGF2R, and PTPRC. CD26 is an intrinsic membrane glycoprotein and a serine exopeptidase that cleaves X-proline dipeptides from the N-terminus of polypeptides. CD26 is expressed specifically in lymphatic vessels but not in blood vessels in the skin, small intestine, esophagus, ovary, breast and prostate glands.

Specificity

Equilibrium disassociation constant (KD) is 5.35 x 10 -11 M

Immunogen

Synthetic peptide corresponding to the extracellular domain of human CD26.

Application

This Anti-CD26 antibody is validated for use in Western Blotting for the detection of CD26.

Target description

~110 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Physical form

Format: Unpurified

Quality

Evaluated by Western Blotting in HUVEC, PC-3, U87 MG, and Ramos cell lysates.

Western Blotting Analysis: A 1:10,000-50,000 dilution of this antibody detected CD26 in HUVEC, PC-3, U87 MG, and Ramos cell lysates.

Other Notes

Concentration: Please refer to lot specific datasheet.

Safety & Documentation

Safety Information

WGK Germany 
WGK 1
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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Peer-Reviewed Papers
15

References

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