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  • MABN50A4 - Anti-Olig2 Antibody, clone 211F1.1, Alexa Fluor488 Conjugate | MABN50A4

MABN50A4 Sigma-Aldrich

Anti-Olig2 Antibody, clone 211F1.1, Alexa Fluor488 Conjugate | MABN50A4

clone 211F1.1, from mouse, ALEXA FLUOR® 488

Synonym: Oligodendrocyte transcription factor 2, Oligo2, Class B basic helix-loop-helix protein 1, bHLHb1, Class E basic helix-loop-helix protein 19, bHLHe19, Protein kinase C-binding protein 2, Protein kinase C-binding protein RACK17

  •  eCl@ss 32160702

  •  NACRES NA.41



Related Categories Alphabetical Index, Antibodies, O, Primary Antibodies
conjugate   ALEXA FLUOR® 488
clone   211F1.1, monoclonal
biological source   mouse
application(s)   immunocytochemistry: suitable
species reactivity   rat, mouse, mouse, human, rat
species reactivity (predicted by homology)   human (based on 100% sequence homology)
shipped in   wet ice
isotype   IgG2a
Quality Level   100
antibody product type   primary antibodies
NCBI accession no.   NP_005797
UniProt accession no.   Q13516
Gene Information   human ... OLIG2(10215)


General description

Oligodendrocyte lineage transcription factor 2 (Olig2) is a protein belonging to group A of the OLIG family of basic helix-loop-helix transcription factors (bHLH). bHLH proteins are divided into 6 groups (A-F), and characterized by their biochemical properties and structure. Olig2 is classified as group A due to its ability to form heterodimers with other bHLH proteins and binding to the E box. Olig2 has a crucial role during development in specifying the final location of motor neurons and oligodendrocytes in the spinal cord, along with the development within the hindbrain of somatic motor neurons. Olig2 expression is observed within oligodendrocytes and in developing astrocytes. Recent studies have shown strong expression of Olig2 in human oligodendrogliomas, primary tumors within the central nervous system, and moderate expression in astrocytomas. These observations have led to the proposal of Olig2 having potential as an oligodendroglioma diagnostic marker.


Recombinant protein corresponding to human Olig2.


Research Category

Research Sub Category
Developmental Neuroscience

Target description

The unconjugated parent antibody (Cat. No. MABN50) has an observed molecular weight at ~37 kDa

Physical form

Protein G Purified

Purified mouse monoclonal IgG2a conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Storage and Stability

Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Legal Information

ALEXA FLUOR is a registered trademark of Life Technologies


Evaluated by Immunocytochemistry in rat oligodendrocyte precursor cells.

Immunocytochemistry Analysis: A 1:100 dilution of this antibody detected Olig2 in rat oligodendrocyte precursor cells.

Analysis Note

Rat oligodendrocyte precursor cells

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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