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SKBM02560 Millipore

Strat-M Membrane, Transdermal Diffusion Test Model, 25mm

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

  •  eCl@ss 32160907

  •  NACRES NB.24

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Properties

Quality Level   400
material   plain filter
  polyethersulfone membrane (synthetic lipid post-treatment)
  polyolefin membrane (synthetic lipid post-treatment)
  white filter
mfr. no.   Millipore
  Strat-M®
diam.   2.5 cm
filter diam.   25 mm
thickness   300 μm
shipped in   ambient

Description

General description

Filter Code: SKBM

Strat-M Membrane for Transdermal Diffusion Testing
Experience the unmatched predictability of Strat-M membrane – a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety and storage limitations.

Strat-M membrane is designed for screening of:
•Active pharmaceutical ingredients (API)
•Cosmetic actives
•Formulations
•Personal care products
•Pesticides and chemicals

Human Skin Correlation
Strat-M membrane is predictive of diffusion in human skin for a wide range of compounds and formulations. Use the Compound Correlation Tool to learn how well Strat-M membrane will work for you.

Reproducible Diffusion Data:
No need to repeat testing each time a new lot of skin arrives in the lab. Strat-M membrane is a highly consistent, engineered material that allows you to compare today’s diffusion data with data you will generate next week, or next month. Furthermore, lot-to-lot consistency brings a new level of clarity to your test data, simplifying your analysis.

Sensitive to Enhancers
Strat-M membrane exhibits differential permeability in the presence of enhancers and is compatible with common formulation formats, so it is appropriate for use during formulation optimization.

Ultimate Experimental Convenience
Strat-M membrane was designed with convenience in mind. The Strat-M membrane is shelf-stable and stocked in the warehouse so procurement and storage is a breeze. Each membrane is individually packaged as precut discs and do not need to be hydrated prior to use. Simply remove the Strat-M membrane disc from its pouch and load into a Franz cell.

Application

Strat-M membrane is a synthetic, non-animal based model for transdermal diffusion testing that is predictive of diffusion in human skin without lot-to-lot variability, safety & storage limitations.

Legal Information

STRAT-M is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles

Articles

Substituting Strat-M® Membrane for Human Skin in Evaluating Effect of Encapsulation on Diffusion of Sunscreen Formulations

Transdermal delivery is commonly used for delivering active skin care compounds. Development of effective sunscreens is a focus of skin care research, given that proper use of sunscreens can prevent ...
Keywords: Absorption, Chromatography, Diffusion, High performance liquid chromatography, Reductions

Use of a Synthetic, Animal-Free Membrane for Transdermal and Topical Delivery of Actives: A Powerful Tool for Pharmaceutical/Personal Care Formulation Development

EuroCosmetics: The International Magazine for Cosmetics & Fragrances November/December 2017 Volume No. 25
Keywords: Adsorption, Cosmetics, Diffusion, Pharmaceutical

Peer-Reviewed Papers
15

References

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