EMAIL THIS PAGE TO A FRIEND
01338 Supelco

Bergamottin

analytical standard

Synonym: Bergamotine, Bergaptin

  • CAS Number 7380-40-7

  • Empirical Formula (Hill Notation) C21H22O4

  • Molecular Weight 338.40

  •  Beilstein/REAXYS Number 1353914

  •  MDL number MFCD00017409

  •  PubChem Substance ID 329747253

  •  NACRES NA.24

Purchase

Properties

Related Categories A - D, Additional Standards, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography,
Quality Level   100
grade   analytical standard
assay   ≥98.0% (HPLC)
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
mp   75-80 °C
Featured Industry   Food and Beverages
storage temp.   2-8°C
SMILES string   C\C(C)=C\CC\C(C)=C\COc1c2C=CC(=O)Oc2cc3occc13
InChI   1S/C21H22O4/c1-14(2)5-4-6-15(3)9-11-24-21-16-7-8-20(22)25-19(16)13-18-17(21)10-12-23-18/h5,7-10,12-13H,4,6,11H2,1-3H3/b15-9+
InChI key   DBMJZOMNXBSRED-OQLLNIDSSA-N

Description

General description

Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities.

Application

Bergamottin may be used as an analytical standard to test its efficacy in the following:
• Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated.
• Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

08168 Timestrip Plus 8 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?