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01518 Supelco

Ginsenoside Rd

analytical standard

Synonym: (3β,12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside, Gypenoside VIII

  • CAS Number 52705-93-8

  • Empirical Formula (Hill Notation) C48H82O18

  • Molecular Weight 947.15

  •  EC Number 258-118-5

  •  NACRES NA.24

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Properties

Related Categories Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography, Cell Biology, E - H,
Quality Level   100
grade   analytical standard
assay   ≥95.0% (HPLC)
shelf life   limited shelf life, expiry date on the label
Featured Industry   Food and Beverages
storage temp.   2-8°C
SMILES string   C\C(C)=C/CC[C@](C)(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@H]2CC[C@]3(C)[C@@H]2[C@H](O)C[C@@H]4[C@@]5(C)CC[C@H](O[C@@H]6O[C@H](CO)[C@@H](O)[C@H](O)[C@H]6O[C@@H]7O[C@H](CO)[C@@H](O)[C@H](O)[C@H]7O)C(C)(C)[C@@H]5CC[C@@]34C
InChI   1S/C48H82O18/c1-21(2)15-22(3)17-48(8,66-43-40(60)37(57)34(54)28(19-50)62-43)24-11-13-47(7)23-9-10-30-45(4,5)31(12-14-46(30,6)25(23)16-26(52)32(24)47)64-44-41(38(58)35(55)29(20-51)63-44)65-42-39(59)36(56)33(53)27(18-49)61-42/h15,22-44,49-60H,9-14,16-20H2,1-8H3/t22?,23?,24-,25?,26-,27+,28+,29+,30?,31?,32+,33+,34+,35+,36-,37-,38-,39+,40+,41+,42-,43-,44-,46+,47+,48-/m0/s1
InChI key   IRBVCFDYIGGFFY-ADSMOORZSA-N

Description

General description

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng. Ginsenoside Rd is the main active component of ginsenosides, having the ability to inhibit Ca2+ influx through receptors and store-operated Ca2+ channel. From neural stem cells, it is seen to enhance astrocyte differentiation. It also reduces the 3-nitropropionic acid-induced motor impairment and cell loss in stratum. It constitutes to one of the major ingredient in total saponin content from Panax notoginseng.

Application

It was used as reference standard in UPLC/TOF-MS analysis of human plasma to determine Ginsenoside metabolites.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

HPLC Analysis Report of Ginsenosides on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis Report of Ginsenosides on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Vitamins

HPLC Analysis of Chinese Ginseng Extract on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Chinese Ginseng Extract on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Separation, Vitamins

HPLC Analysis of Ginsenoside Standards on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ginsenoside Standards on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Separation, Vitamins

HPLC Analysis of Ginsenosides on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ginsenosides on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Vitamins

High-Performance Thin-Layer Chromatography: A Fast and Efficient Fingerprint Analysis Method for Medicinal Plants

Ginsenosides are triterpene saponins. Most ginsenosides are composed of a dammarane skeleton (17 carbons in a four-ring structure) with various sugar moieties (e.g. glucose, rhamnose, xylose and arab...
Keywords: Calorimetry, Chromatography, Derivatizations, Sample preparations, Separation, Thin layer chromatography

Separation of Ginsenosides in Panax Quinquefolius (American Ginseng)

Ginsenosides are mainly found in ginseng plants (genus Panax), widely used as a herbal medicine around the world but primarily in Asian cultures. Most ginsenosides are members of the dammarane family...
Keywords: Chromatography, Diabetes, Nuclear magnetic resonance spectroscopy, Pharmaceutical, Separation, Sonication, Thin layer chromatography

Peer-Reviewed Papers
15

References

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