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Ginsenoside Rf

primary reference standard

Synonym: (3β,6α,12β)-3,12,20-Trihydroxydammar-24-en-6-yl 2-O-β-D-glucopyranosyl-β-D-glucopyranoside, Panaxoside Rf

  • CAS Number 52286-58-5

  • Empirical Formula (Hill Notation) C42H72O14

  • Molecular Weight 801.01

  •  MDL number MFCD00210509

  •  PubChem Substance ID 329747330

  •  NACRES NA.24

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Properties

Related Categories Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography, Cell Biology, E - H,
grade   primary reference standard
CofA   certificate is enclosed in each package
shelf life   limited shelf life, expiry date on the label
Featured Industry   Food and Beverages
storage temp.   −20°C
SMILES string   [H][C@]1(O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)O[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)O[C@@]2([H])O[C@H]3C[C@]4(C)[C@]([H])(C[C@@H](O)[C@]5([H])[C@]([H])(CC[C@@]45C)[C@@](C)(O)CC\C=C(/C)C)[C@@]6(C)CC[C@H](O)C(C)(C)[C@]36[H]
InChI   1S/C42H72O14/c1-20(2)10-9-13-42(8,52)21-11-15-40(6)28(21)22(45)16-26-39(5)14-12-27(46)38(3,4)35(39)23(17-41(26,40)7)53-37-34(32(50)30(48)25(19-44)55-37)56-36-33(51)31(49)29(47)24(18-43)54-36/h10,21-37,43-52H,9,11-19H2,1-8H3/t21-,22+,23-,24+,25+,26+,27-,28-,29+,30+,31-,32-,33+,34+,35-,36-,37+,39+,40+,41+,42-/m0/s1
InChI key   UZIOUZHBUYLDHW-XUBRWZAZSA-N

Description

General description

Ginsenoside is a steroid-like molecular component having gonane steroid nucleus along with different sugar moieties attached to them found in the roots of Panax ginseng. Ginsenoside Rf, a variety of ginseng saponins with attached sugars moieties which inhibits the Ca2+ channels present in primary sensory neurons.

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

It may be used as reference standard in HPLC-MS/MS analysis of human plasma to determine Ginsenosides from herbal products containing Panax ginseng and Panax quinquefolius.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
LY9536900
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

HPLC Analysis of Ginsenosides on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Ginsenosides on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Vitamins

High-Performance Thin-Layer Chromatography: A Fast and Efficient Fingerprint Analysis Method for Medicinal Plants

Ginsenosides are triterpene saponins. Most ginsenosides are composed of a dammarane skeleton (17 carbons in a four-ring structure) with various sugar moieties (e.g. glucose, rhamnose, xylose and arab...
Keywords: Calorimetry, Chromatography, Derivatizations, Sample preparations, Separation, Thin layer chromatography

Separation of Ginsenosides in Panax Quinquefolius (American Ginseng)

Ginsenosides are mainly found in ginseng plants (genus Panax), widely used as a herbal medicine around the world but primarily in Asian cultures. Most ginsenosides are members of the dammarane family...
Keywords: Chromatography, Diabetes, Nuclear magnetic resonance spectroscopy, Pharmaceutical, Separation, Sonication, Thin layer chromatography

Peer-Reviewed Papers
15

References

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