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02150595 Sigma-Aldrich

Osthole

primary reference standard

Synonym: 7-Methoxy-8-(3-methyl-2-butenyl)coumarin, 7-Methoxy-8-isopentenylcoumarin, Osthol

  • CAS Number 484-12-8

  • Empirical Formula (Hill Notation) C15H16O3

  • Molecular Weight 244.29

  •  MDL number MFCD00076049

  •  PubChem Substance ID 329747396

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Phenylpropanes, Phyto Primary Reference Standards and Extracts (Secondary Reference Standards), Phytochemical Standards More...
grade   primary reference standard
InChI Key   MBRLOUHOWLUMFF-UHFFFAOYSA-N
CofA   certificate is enclosed in each package
shelf life   limited shelf life, expiry date on the label
Featured Industry   Food and Beverages

Description

Application

Reference Standard in the analysis of herbal medicinal products

Biochem/physiol Actions

Active constituent of Cnidium monnieri, a traditional Chinese medicine used for its anti-inflammatory, analgesic, and anti-lipedemic activities. Dramatically decreased lipid accumulation in a quail model. Its neuroprotective effect on MPP(+)-induced cytotoxicity in PC12 cells supports the use of osthole as a therapeutic agent for the treatment of neurodegenerative disorders. Suppression of fatty acid synthase expression in HER2-overexpressing breast cancer cells indicates osthole as a promising agent for chemotherapy.

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
GN7700000
Protocols & Articles
Peer-Reviewed Papers
15

References

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