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03395 Sigma-Aldrich

Poly(ethylene glycol)

tested according to Ph Eur, 1,000

Synonym: Macrogol 1000, PEG

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Properties

Related Categories Analytical/Chromatography, Essential Chemicals, Materials Science, PEG and Oligo Ethylene Glycol, Pharmacopoeia,
Agency/Method   tested according to Ph Eur
Quality Level   100
form   waxy solid
mol wt   950-1050
solubility   aliphatic hydrocarbons: slightly soluble
  organic solvents: soluble
Featured Industry   Pharmaceutical (small molecule)
SMILES string   C(CO)O
InChI   1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key   LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

Application

Poly(ethylene glycol) is a chemical fusogen, which mediates the premature chromosome condensation induction in human and rat lymphocytes as well as in rodent spleen cells, and spleen and whole body cells of newborn mice.

Biochem/physiol Actions

Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.

Preparation Note

Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
TQ3500000
Flash Point(F) 
444.2 °F - closed cup
Flash Point(C) 
229.00 °C - closed cup

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Peer-Reviewed Papers
15

References

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