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03557 Sigma-Aldrich

Poly(ethylene glycol)

tested according to Ph Eur, 35,000

Synonym: Macrogol 35,000, PEG

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Properties

Related Categories Analytical/Chromatography, Essential Chemicals, Materials Science, PEG and Oligo Ethylene Glycol, Pharmacopoeia,
Agency/Method   tested according to Ph Eur
Quality Level   200
form   powder
mol wt   ~35000
solubility   aliphatic hydrocarbons: slightly soluble
  organic solvents: soluble
Featured Industry   Pharmaceutical (small molecule)
SMILES string   C(CO)O
InChI   1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2
InChI key   LYCAIKOWRPUZTN-UHFFFAOYSA-N

Description

Application

Poly (ethylene glycol) can be used as a test compound utilized in the overproduction and purification of recombinant Lactobacillus reuteri LrNDT. It can also be used for concentrating the mutants with lower secretion levels used in ELISAs for the quantitation of shgp190 and of the LIF/shgp190 complexes.

Biochem/physiol Actions

Polyethylene glycol (PEG) is a condensation polymer of ethylene oxide and water. It enhances the refolding of extracted proteins. This enables characterization of crystallized proteins.

Preparation Note

Poly(ethylene glycol) dissolves in many organic solvents and is readily soluble in aromatic hydrocarbons. It also slightly dissolves in aliphatic hydrocarbons.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
TQ3500000
Flash Point(F) 
444.2 °F - closed cup
Flash Point(C) 
229.00 °C - closed cup

Documents

Certificate of Analysis (COA)

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Single- & multi-channel pipettes from BRAND
Protocols & Articles

Articles

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

Peer-Reviewed Papers
15

References

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