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03910590 Sigma-Aldrich

(±)-Catechin hydrate

primary reference standard

Synonym: trans-3,3′,4′,5,7-Pentahydroxyflavane, trans-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

  • CAS Number 7295-85-4 (anhydrous)

  • Empirical Formula (Hill Notation) C15H14O6 · xH2O

  • Molecular Weight 290.27 (anhydrous basis)

  •  Beilstein/REAXYS Number 92762

  •  EC Number 205-825-1

  •  MDL number MFCD00149354

  •  PubChem Substance ID 329747836

  •  NACRES NA.24

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Properties

Related Categories A - D, Acacia, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography,
grade   primary reference standard
assay   >90.0%
form   powder
CofA   certificate is enclosed in each package
shelf life   limited shelf life, expiry date on the label
Featured Industry   Food and Beverages
storage temp.   −20°C
SMILES string   [H]O[H].O[C@H]1Cc2c(O)cc(O)cc2O[C@@H]1c3ccc(O)c(O)c3
InChI   1S/C15H14O6.H2O/c16-8-4-11(18)9-6-13(20)15(21-14(9)5-8)7-1-2-10(17)12(19)3-7;/h1-5,13,15-20H,6H2;1H2/t13-,15+;/m0./s1
InChI key   OFUMQWOJBVNKLR-NQQJLSKUSA-N

Description

General description

Catechin hydrate, a flavononol, belongs to the class of flavonoids. It is present in abundance in Siberian larch (Larix sibirica) and in silymarin extract of milk thistle seeds. Its potent chemopreventive action by virtue of the regulation of genes through the ARE-dependent pathway has been widely investigated. It also shows potential antioxidant activity against ovarian cancer cell growth, cellular melanogenesis, human breast cancer, etc.

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Catechin hydrate may be used as a reference standard for the determination of the analyte in walnut leaves by high-performance liquid chromatography (HPLC).

Biochem/physiol Actions

Polyphenolic antioxidant. Used in traditional Chinese medicine.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DJ3450000
Protocols & Articles
Peer-Reviewed Papers
15

References

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