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04646 Sigma-Aldrich

Hamamelitannin

≥98.0% (HPLC)

Synonym: 2-C-(Hydroxymethyl)-D-ribofuranose 2′,5-digallate, Hamamelofuranose 2′,5-digallate

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Properties

Related Categories Additional Standards, Alcohols, Alphabetical Index of Phytochemical Standards, Analytical Standards, Analytical/Chromatography,
Quality Level   100
assay   ≥98.0% (HPLC)
form   powder or crystals
Featured Industry   Food and Beverages
storage temp.   2-8°C
SMILES string   OC1O[C@H](COC(=O)c2cc(O)c(O)c(O)c2)[C@@H](O)[C@]1(O)COC(=O)c3cc(O)c(O)c(O)c3
InChI   1S/C20H20O14/c21-9-1-7(2-10(22)14(9)25)17(28)32-5-13-16(27)20(31,19(30)34-13)6-33-18(29)8-3-11(23)15(26)12(24)4-8/h1-4,13,16,19,21-27,30-31H,5-6H2/t13-,16-,19?,20-/m1/s1
InChI key   FEPAFOYQTIEEIS-IZUGRSKYSA-N

Description

Application

Hamamelitannin can be used to study chromatography, aromatics, esters, hamamelis, heterocyclics, natural compounds, phenols, phytopharma standards, polyhydroxy compounds and tannins. Hamamelitannin significantly reduces biofilm metabolic activity of the following bacteria: Staphylococcus epidermidis, Staphylococcus aureus, Acinetobacter baumannii and Candida albicans strains. Hamamelitannin displays specific cytotoxic activity against colon cancer cells. Hamamelitannin has been used in a study to determine that quorum sensing inhibitors increase the success of antibiotic treatment by increasing the susceptibility of bacterial biofilms and/or by increasing host survival following infection.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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