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3,4-Dihydroxybenzoic acid

analytical standard

Synonym: Protocatechuic acid

  • CAS Number 99-50-3

  • Linear Formula (HO)2C6H3CO2H

  • Molecular Weight 154.12

  •  Beilstein/REAXYS Number 1448841

  •  EC Number 202-760-0

  •  MDL number MFCD00002509

  •  PubChem Substance ID 329748656

  •  NACRES NA.24

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Description

General description

3,4-Dihydroxybenzoic acid is a catabolite of epinephrine. It is a phenolic compound and an important constituent of lignin present in wine, green and black tea, and herbal medicines, which exhibits anti-inflammatory and antitumor promotion. 3,4-Dihydroxybenzoic acid is also a model matrix for ionization of peptides, proteins and carbohydrates in the MALDI (matrix-assisted laser desorption ionization mass spectroscopy) technique.

Application

3,4-Dihydroxybenzoic acid may be used as a reference standard for the determination of:
• Phenols in biomass pre-treatment hydrolysates by high-performance liquid chromatography method.
• 3,4-Dihydroxybenzoic acid in wine by high-performance liquid chromatography with a microbore column.

Biochem/physiol Actions

Chemopreventive in several animal models of carcinogenesis. Blocks cell proliferation in the post-initiation phase.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
UL0560000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

MSMLS Online Plate Map

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Keywords: Mass spectrometry, Metabolites

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Peer-Reviewed Papers
15

References

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